Busting foes of post-publication peer review of a psychotherapy study

title_vigilante_blu-rayAs described in the last issue of Mind the Brain, peaceful post-publication peer reviewers (PPPRs) were ambushed by an author and an editor. They used the usual home team advantages that journals have – they had the last word in an exchange that was not peer-reviewed.

As also promised, I will team up in this issue with Magneto to bust them.

Attacks on PPPRs threaten a desperately needed effort to clean up the integrity of the published literature.

The attacks are getting more common and sometimes vicious. Vague threats of legal action caused an open access journal to remove an article delivering fair and balanced criticism.

In a later issue of Mind the Brain, I will describe an  incident in which authors of a published paper had uploaded their data set, but then  modified it without notice after PPPRs used the data for re-analyses. The authors then used the modified data for new analyses and then claimed the PPPRs were grossly mistaken. Fortunately, the PPPRs retained time stamped copies of both data sets. You may like to think that such precautions are unnecessary, but just imagine what critics of PPPR would be saying if they had not saved this evidence.

Until journals get more supportive of post publication peer review, we need repeated vigilante actions, striking from Twitter, Facebook pages, and blogs. Unless readers acquire basic critical appraisal skills and take the time to apply them, they will have to keep turning to the social media for credible filters of all the crap that is flooding the scientific literature.

MagnetoYardinI’ve enlisted Magneto because he is a mutant. He does not have any extraordinary powers of critical appraisal. To the contrary, he unflinchingly applies what we should all acquire. As a mutant, he can apply his critical appraisal skills without the mental anguish and physiological damage that could beset humans appreciating just how bad the literature really is. He doesn’t need to maintain his faith in the scientific literature or the dubious assumption that what he is seeing is just a matter of repeat offender authors, editors, and journals making innocent mistakes.

Humans with critical appraisal risk demoralization and too often shirk from the task of telling it like it is. Some who used their skills too often were devastated by what they found and fled academia. More than a few are now working in California in espresso bars and escort services.

Thank you, Magneto. And yes, I again apologize for having tipped off Jim Coan about our analyses of his spinning and statistical manipulations of his work to get newsworthy finding. Sure, it was an accomplishment to get a published apology and correction from him and Susan Johnson. I am so proud of Coan’s subsequent condemnation of me on Facebook as the Deepak Chopra of Skepticism  that I will display it as an endorsement on my webpage. But it was unfortunate that PPPRs had to endure his nonsensical Negative Psychology rant, especially without readers knowing what precipitated it.

shakespeareanThe following commentary on the exchange in Journal of Nervous and Mental Disease makes direct use of your critique. I have interspersed gratuitous insults generated by Literary Genius’ Shakespearean insult generator and Reocities’ Random Insult Generator.

How could I maintain the pretense of scholarly discourse when I am dealing with an author who repeatedly violates basic conventions like ensuring tables and figures correspond to what is claimed in the abstract? Or an arrogant editor who responds so nastily when his slipups are gently brought to his attention and won’t fix the mess he is presenting to his readership?

As a mere human, I needed all the help I could get in keeping my bearings amidst such overwhelming evidence of authorial and editorial ineptness. A little Shakespeare and Monty Python helped.

The statistical editor for this journal is a saucy full-gorged apple-john.

 

Cognitive Behavioral Techniques for Psychosis: A Biostatistician’s Perspective

Domenic V. Cicchetti, PhD, quintessential  biostatistician
Domenic V. Cicchetti, PhD, quintessential biostatistician

Domenic V. Cicchetti, You may be, as your website claims

 A psychological methodologist and research collaborator who has made numerous biostatistical contributions to the development of major clinical instruments in behavioral science and medicine, as well as the application of state-of-the-art techniques for assessing their psychometric properties.

But you must have been out of “the quintessential role of the research biostatistician” when you drafted your editorial. Please reread it. Anyone armed with an undergraduate education in psychology and Google Scholar can readily cut through your ridiculous pomposity, you undisciplined sliver of wild belly-button fluff.

You make it sound like the Internet PPPRs misunderstood Jacob Cohen’s designation of effect sizes as small, medium, and large. But if you read a much-accessed article that one of them wrote, you will find a clear exposition of the problems with these arbitrary distinctions. I know, it is in an open access journal, but what you say is sheer bollocks about it paying reviewers. Do you get paid by Journal of Nervous and Mental Disease? Why otherwise would you be a statistical editor for a journal with such low standards? Surely, someone who has made “numerous biostatistical contributions” has better things to do, thou dissembling swag-bellied pignut.

More importantly, you ignore that Jacob Cohen himself said

The terms ‘small’, ‘medium’, and ‘large’ are relative . . . to each other . . . the definitions are arbitrary . . . these proposed conventions were set forth throughout with much diffidence, qualifications, and invitations not to employ them if possible.

Cohen J. Statistical power analysis for the behavioural sciences. Second edition, 1988. Hillsdale, NJ: Lawrence Earlbaum Associates. p. 532.

Could it be any clearer, Dommie?

Click to enlarge

You suggest that the internet PPPRs were disrespectful of Queen Mother Kraemer in not citing her work. Have you recently read it? Ask her yourself, but she seems quite upset about the practice of using effects generated from feasibility studies to estimate what would be obtained in an adequately powered randomized trial.

Pilot studies cannot estimate the effect size with sufficient accuracy to serve as a basis of decision making as to whether a subsequent study should or should not be funded or as a basis of power computation for that study.

Okay you missed that, but how about:

A pilot study can be used to evaluate the feasibility of recruitment, randomization, retention, assessment procedures, new methods, and implementation of the novel intervention. A pilot study is not a hypothesis testing study. Safety, efficacy and effectiveness are not evaluated in a pilot. Contrary to tradition, a pilot study does not provide a meaningful effect size estimate for planning subsequent studies due to the imprecision inherent in data from small samples. Feasibility results do not necessarily generalize beyond the inclusion and exclusion criteria of the pilot design.

A pilot study is a requisite initial step in exploring a novel intervention or an innovative application of an intervention. Pilot results can inform feasibility and identify modifications needed in the design of a larger, ensuing hypothesis testing study. Investigators should be forthright in stating these objectives of a pilot study.

Dommie, although you never mention it, surely you must appreciate the difference between a within-group effect size and a between-group effect size.

  1. Interventions do not have meaningful effect sizes, between-group comparisons do.
  2. As I have previously pointed out

 When you calculate a conventional between-group effect size, it takes advantage of randomization and controls for background factors, like placebo or nonspecific effects. So, you focus on what change went on in a particular therapy, relative to what occurred in patients who didn’t receive it.

Turkington recruited a small, convenience sample of older patients from community care who averaged over 20 years of treatment. It is likely that they were not getting much support and attention anymore, whether or not they ever were. The intervention that Turkington’s study provided that attention. Maybe some or all of any effects were due to simply compensating for what was missing from from inadequate routines care. So, aside from all the other problems, anything going on in Turkington’s study could have been nonspecific.

Recall that in promoting his ideas that antidepressants are no better than acupuncture for depression, Irving Kirsh tried to pass off within-group as equivalent to between-group effect sizes, despite repeated criticisms. Similarly, long term psychodynamic psychotherapists tried to use effect sizes from wretched case series for comparison with those obtained in well conducted studies of other psychotherapies. Perhaps you should send such folks a call for papers so that they can find an outlet in Journal of Nervous and Mental Disease with you as a Special Editor in your quintessential role as biostatistician.

Douglas Turkington’s call for a debate

Professor Douglas Turkington: "The effect size that got away was this big."
Professor Douglas Turkington: “The effect size that got away was this big.”

Doug, as you requested, I sent you a link to my Google Scholar list of publications. But you still did not respond to my offer to come to Newcastle and debate you. Maybe you were not impressed. Nor did you respond to Keith Law’s repeated request to debate. Yet you insulted internet PPPR Tim Smits with the taunt,

Click to Enlarge

 

You congealed accumulation of fresh cooking fat.

I recommend that you review the recording of the Maudsley debate. Note how the moderator Sir Robin Murray boldly announced at the beginning that the vote on the debate was rigged by your cronies.

Do you really think Laws and McKenna got their asses whipped? Then why didn’t you accept Laws’ offer to debate you at a British Psychological Society event, after he offered to pay your travel expenses?

High-Yield Cognitive Behavioral Techniques for Psychosis Delivered by Case Managers…

Dougie, we were alerted that bollacks would follow with the “high yield” of the title. Just what distinguishes this CBT approach from any other intervention to justify “high yield” except your marketing effort? Certainly, not the results you have obtained from an earlier trial, which we will get to.

Where do I begin? Can you dispute what I said to Dommie about the folly of estimating effect sizes for an adequately powered randomized trial from a pathetically small feasibility study?

I know you were looking for a convenience sample, but how did you get from Newcastle, England to rural Ohio and recruit such an unrepresentative sample of 40 year olds with 20 years of experience with mental health services? You don’t tell us much about them, not even a breakdown of their diagnoses. But would you really expect that the routine care they were currently receiving was even adequate? Sure, why wouldn’t you expect to improve upon that with your nurses? But would you be demonstrating?

insult 1

 

The PPPR boys from the internet made noise about Table 2 and passing reference to the totally nude Figure 5 and how claims in the abstract had no apparent relationship to what was presented in the results section. And how nowhere did you provide means or standard deviations. But they did not get to Figure 2 Notice anything strange?

figure 2Despite what you claim in the abstract, none of the outcomes appear significant. Did you really mean standard error of measurement (SEMs), not standard deviations (SDs)? People did not think so to whom I showed the figure.

mike miller

 

And I found this advice on the internet:

If you want to create persuasive propaganda:

If your goal is to emphasize small and unimportant differences in your data, show your error bars as SEM,  and hope that your readers think they are SD.

If our goal is to cover-up large differences, show the error bars as the standard deviations for the groups, and hope that your readers think they are a standard errors.

Why did you expect to be able to talk about effect sizes of the kind you claim you were seeking? The best meta analysis suggests an effect size of only .17 with blind assessment of outcome. Did you expect that unblinding assessors would lead to that much more improvement? Oh yeh, you cited your own previous work in support:

That intervention improved overall symptoms, insight, and depression and had a significant benefit on negative symptoms at follow-up (Turkington et al., 2006).

Let’s look at Table 1 from Turkington et al., 2006.

A consistent spinning of results

Table 1 2006

Don’t you just love those three digit significance levels that allow us to see that p =.099 for overall symptoms meets the apparent criteria of p < .10 in this large sample? Clever, but it doesn’t work for depression with p = .128. But you have a track record of being sloppy with tables. Maybe we should give you the benefit of a doubt and ignore the table.

But Dougie, this is not some social priming experiment with college students getting course credit. This is a study that took up the time of patients with serious mental disorder. You left some of them in the squalor of inadequate routine care after gaining their consent with the prospect that they might get more attention from nurses. And then with great carelessness, you put the data into tables that had no relationship to the claims you were making in the abstract. Or in your attempts to get more funding for future such ineptitude. If you drove your car like you write up clinical trials, you’d lose your license, if not go to jail.

insult babbling

 

 

The 2014 Lancet study of cognitive therapy for patients with psychosis

Forgive me that I missed until Magneto reminded me that you were an author on the, ah, controversial paper

Morrison, A. P., Turkington, D., Pyle, M., Spencer, H., Brabban, A., Dunn, G., … & Hutton, P. (2014). Cognitive therapy for people with schizophrenia spectrum disorders not taking antipsychotic drugs: a single-blind randomised controlled trial. The Lancet, 383(9926), 1395-1403.

But with more authors than patients remaining in the intervention group at follow up, it is easy to lose track.

You and your co-authors made some wildly inaccurate claims about having shown that cognitive therapy was as effective as antipsychotics. Why, by the end of the trial, most of the patients remaining in follow up were on antipsychotic medication. Is that how you obtained your effectiveness?

In our exchange of letters in The Lancet, you finally had to admit

We claimed the trial showed that cognitive therapy was safe and acceptable, not safe and effective.

Maybe you should similarly be retreating from your claims in the Journal of Nervous and Mental Disease article? Or just take refuge in the figures and tables being uninterpretable.

No wonder you don’t want to debate Keith Laws or me.

insult 3

 

 

A retraction for High-Yield Cognitive Behavioral Techniques for Psychosis…?

The Turkington article meets the Committee on Publication Ethics (COPE) guidelines for an immediate retraction (http://publicationethics.org/files/retraction%20guidelines.pdf).

But neither a retraction nor even a formal expression of concern has appeared.

Toilet-outoforderMaybe matters can be left as they now are. In the social media, we can point to the many problems of the article like a clogged toilet warning that Journal of Nervous and Mental Disease is not a fit place to publish – unless you are seeking exceeding inept or nonexistent editing and peer review.

 

 

 

Vigilantes can periodically tweet Tripadvisor style warnings, like

toilets still not working

 

 

Now, Dommie and Dougie, before you again set upon some PPPRs just trying to do their jobs for little respect or incentive, consider what happened this time.

Special thanks are due for Magneto, but Jim Coyne has sole responsibility for the final content. It  does not necessarily represent the views of PLOS blogs or other individuals or entities, human or mutant.

Sordid tale of a study of cognitive behavioral therapy for schizophrenia gone bad

What motivates someone to publish that paper without checking it? Laziness? Naivety? Greed? Now that’s one to ponder. – Neuroskeptic, Science needs vigilantes.

feared_and_hated_by_a_world_they_have_sworn_to_pro_by_itomibhaa-d4kx9bd.pngWe need to

  • Make the world safe for post-publication peer review (PPR) commentary.
  • Ensure appropriate rewards for those who do it.
  • Take action against those who try to make life unpleasant for those who are toil hard for a scientific literature that is more trustworthy.

In this issue of Mind the Brain, I set the stage for my teaming up with Magneto to bring some bullies to justice.

The background tale of a modest study of cognitive behavior therapy (CBT) for patients with schizophrenia has been told in bits and pieces elsewhere.

The story at first looked like it was heading for a positive outcome more worthy of a blog post than the shortcomings of a study in an obscure journal. The tale would go

A group organized on the internet called attention to serious flaws in the reporting of a study. We then witnessed the self-correcting of science in action.

If only this story was complete and accurately described scientific publishing today

Daniel Lakens’ blog post, How a Twitter HIBAR [Had I Been A Reviewer] ends up as a published letter to the editor recounts the story beginning with expressions of puzzlement and skepticism on Twitter.

Gross errors were made in a table and a figure. These were bad enough in themselves, but seemed to point to reported results not seem supporting the claims made in the article.

A Swedish lecturer blogged Through the looking glass into an oddly analyzed clinical paper .

Some of those involved in the Twitter exchange banded together in writing a letter to the editor.

Smits, T., Lakens, D., Ritchie, S. J., & Laws, K. R. (2014). Statistical errors and omissions in a trial of cognitive behavior techniques for psychosis: commentary on Turkington et al. The Journal of Nervous and Mental Disease, 202(7), 566.

Lakens explained in his blog

Now I understand that getting criticism on your work is never fun. In my personal experience, it very often takes a dinner conversation with my wife before I’m convinced that if people took the effort to criticize my work, there must be something that can be improved. What I like about this commentary is that is shows how Twitter is making post-publication reviews possible. It’s easy to get in contact with other researchers to discuss any concerns you might have (as Keith did in his first Tweet). Note that I have never met any of my co-authors in real life, demonstrating how Twitter can greatly extend your network and allows you to meet interesting and smart people who share your interests. Twitter provides a first test bed for your criticisms to see if they hold up (or if the problem lies in your own interpretation), and if a criticism is widely shared, can make it fun to actually take the effort to do something about a paper that contains errors.

Furthermore,

It might be slightly weird that Tim, Stuart, and myself publish a comment in the Journal of Nervous and Mental Disease, a journal I guess none of us has ever read before. It also shows how Twitter extends the boundaries between scientific disciplines. This can bring new insights about reporting standards  from one discipline to the next. Perhaps our comment has made researchers, reviewers, and editors who do research on cognitive behavioral therapy aware of the need to make sure they raise the bar on how they report statistics (if only so pesky researchers on Twitter leave you alone!). I think this would be great, and I can’t wait until researchers from another discipline point out statistical errors in my own articles that I and my closer peers did not recognize, because anything that improves the way we do science (such as Twitter!) is a good thing.

Hindsight: If the internet group had been the original reviewers of the article…

The letter was low key and calmly pointed out obvious errors. You can see it here. Tim Smit’s blog Don’t get all psychotic on this paper: Had I (or we) Been A Reviewer (HIBAR) describes what had to be left out to keep within the word limit.

the actual table originalTable 2 had lots of problems –

  • The confidence intervals were suspiciously wide.
  • The effect sizes seemed too large for what the modest sample size should yield.
  • The table was inconsistent with information in the abstract.
  • Neither they table nor the accompanying text had any test of significance nor reporting of means and standard deviations.
  • Confidence intervals for two different outcomes were identical, yet one had the same value for its effect size as its lower bound.

Figure 5 Click to Enlarge

Figure 5 was missing labels and definitions on both axes, rendering it uninterpretable. Duh?

The authors of the letter were behaving like a blue helmeted international peacekeeping force, not warriors attacking bad science.

peacekeepersBut you don’t send peacekeeping troops into an active war zone.

In making recommendations, the Internet group did politely introduce the R word:

We believe the above concerns mandate either an extensive correction, or perhaps a retraction, of the article by Turkington et al. (2014). At the very least, the authors should reanalyze their data and report the findings in a transparent and accurate manner.

Fair enough, but I doubt the authors of the letter appreciated how upsetting this reasonable advice was or anticipated what reaction would be coming.

A response from an author of the article and a late night challenge to debate

The first author of the article published a reply

Turkington, D. (2014). The reporting of confidence intervals in exploratory clinical trials and professional insecurity: a response to Ritchie et al. The Journal of Nervous and Mental Disease, 202(7), 567.

He seemed to claim to re-examine the study data and

  • The findings were accurately reported.
  • A table of means and standard deviations was unnecessary because of the comprehensive reporting of confidence intervals and p-values in the article.
  • The missing details from the figure were self-evident.

The group who had assembled on the internet was not satisfied. An email exchange with Turkington and the editor of the journal confirmed that Turkington had not actually re-examined the raw file data, but only a summary with statistical tables.

The group requested the raw data. In a subsequent letter to the editor, they would describe Turkington as timely the providing the data, but the exchange between them was anything but cordial. Turkington at first balked, saying that the data were not readily available because the statistician had retired. He nonetheless eventually provided the data, but not before first sending off a snotty email –

Click to Enlarge
Click to Enlarge

Tim Smit declined:

Dear Douglas,

Thanks for providing the available data as quick as possible. Based on this and the tables in the article, we will try to reconstruct the analysis and evaluate our concerns with it.

With regard to your recent invitation to “slaughter” me at Newcastle University, I politely want to decline that invitation. I did not have any personal issue in mind when initiating the comment on your article, so a personal attack is the least of my priorities. It is just from a scientific perspective (but an outsider to the research topic) that I was very confused/astonished about the lack of reporting precision and what appears to be statistical errors. So, if our re-analysis confirms that first perception, then I am of course willing to accept your invitation at Newcastle university to elaborate on proper methodology in intervention studies, since science ranks among the highest of my priorities.

Best regards,

Tim Smits

When I later learned of this email exchange, I wrote to Turkington and offered to go to Newcastle to debate either as Tim Smits’ second or to come alone. Turkington asked me to submit my CV to show that I wasn’t a crank. I complied, but he has yet to accept my offer.

A reanalysis of the data and a new table

Smits, T., Lakens, D., Ritchie, S. J., & Laws, K. R. (2015). Correcting Errors in Turkington et al.(2014): Taking Criticism Seriously. The Journal of nervous and mental disease, 203(4), 302-303.

The group reanalyzed the data and the title of their report leaked some frustration.

We confirmed that all the errors identified by Smits et al. (2014) were indeed errors. In addition, we observed that the reported effect sizes in Turkington et al. (2014) were incorrect by a considerable margin. To correct these errors, Table 2 and all the figures in Turkington et al. (2014) need to be changed.

The sentence in the Abstract where effect sizes are specified needs to be rewritten.

A revised table based on their reanalyses was included:

new tableGiven the recommendation of their first letter was apparently dismissed –

To conclude, our recommendation for the Journal and the authors would now be to acknowledge that there are clear errors in the original Turkington et al. (2014) article and either accept our corrections or publish their own corrigendum. Moreover, we urge authors, editors, and reviewers to be rigorous in their research and reviewing, while at the same time being eager to reflect on and scrutinize their own research when colleagues point out potential errors. It is clear that the authors and editors should have taken more care when checking the validity of our criticisms. The fact that a rejoinder with the title “A Response to Ritchie et al. [sic]” was accepted for publication in reply to a letter by Smits et al. (2014) gives the impression that our commentary did not receive the attention it deserved. If we want science to be self-correcting, it is important that we follow ethical guidelines when substantial errors in the published literature are identified.

Sound and fury signifying nothing

Publication of their letter was accompanied by a blustery commentary from the statistical editor for the journal full of innuendo and pomposity.

quote-a-harmless-hilarity-and-a-buoyant-cheerfulness-are-not-infrequent-concomitants-of-genius-and-we-charles-caleb-colton-294969

Cicchetti, D. V. (2015). Cognitive Behavioral Techniques for Psychosis: A Biostatistician’s Perspective. The Journal of Nervous and Mental Disease, 203(4), 304-305.

He suggested that the team assembled on the internet

reanalyzed the data of Turkington et al. on the basis that it contained some serious errors that needed to be corrected. They also reported that the statistic that Turkington et al. had used to assess effect sizes (ESs) was an inappropriate metric.

Well, did Turkington’s table contain errors and was the metric inappropriate? If so, was a formal correction or even retraction needed? Cicchetti reproduced the internet groups’ table, but did not immediately offer his opinion. So, the uncorrected article stands as published. Interested persons downloading it from behind the journal’s paywall won’t be alerted to the controversy.

hello potInstead of dealing with the issues at hand, Cicchetti launched into an irrelevant lecture about Jacob Cohen’s arbitrary designation of effect sizes as small, medium, or large. Anything he said had already appeared clearer and more accurately in an article by Daniel Laken, one of the internet group authors. Cicchetti cited that article, but only as a basis for libeling the open access journal in which it appeared.

To be perfectly candid, the reader needs to be informed that the journal that published the Lakens (2013) article, Frontiers in Psychology, is one of an increasing number of journals that charge exorbitant publication fees in exchange for free open access to published articles. Some of the author costs are used to pay reviewers, causing one to question whether the process is always unbiased, as is the desideratum. For further information, the reader is referred to the following Web site: http://www.frontiersin.org/Psychology/fees.

love pomposityCicchetti further chastised the internet group for disrespecting the saints of power analysis.

As an additional comment, the stellar contributions of Helena Kraemer and Sue Thiemann (1987) were noticeable by their very absence in the Smits et al. critique. The authors, although genuinely acknowledging the lasting contributions of Jacob Cohen to our understanding of ES and power analysis, sought to simplify the entire enterprise

Jacob Cohen is dead and cannot speak. But good Queen Mother Helena is very much alive and would surely object to being drawn into this nonsense. I encourage Cicchetti to ask what she thinks.

Ah, but what about the table based on the re-analyses of the internet group that Cicchetti had reproduced?

The reader should also be advised that this comment rests upon the assumption that the revised data analyses are indeed accurate because I was not privy to the original data.

Actually, when Turkington sent the internet group the study data, he included Cicchetti in the email.

The internet group experienced one more indignity from the journal that they had politely tried to correct. They had reproduced Turkington’s original table in their letter. The journal sent them an invoice for 106 euros because the table was copyrighted. It took a long email exchange before this billing was rescinded.

Science Needs Vigilantes

Imagine a world where we no longer depend on a few cronies of an editor to decide once and forever the value of a paper. This would replace the present order in which much of the scientific literature is untrustworthy, where novelty and sheer outrageousness of claims are valued over robustness.

Imagine we have constructed a world where post publication commentary is welcomed and valued. Data are freely available for reanalysis and the rewards are there for performing those re-analyses.

We clearly are not there yet and certainly not with this flawed article. The sequence of events that I have described has so far not produced a correction of a paper. As it stands, the paper concludes that nurses can and should be given a brief training that will allow them to effectively treat patients with severe and chronic mental disorder. This paper encourages actions that may put such patients and society at risk because of ineffectual and neglectful treatment.

The authors of the original paper and the editor responded with dismissal of the criticisms, ridicule, and, the editor at least, libeling open access journals. Obviously, we have not reached the point at which those willing to re-examine and if necessary, re-analyze data, are appropriately respected and protected from unfair criticism. The current system of publishing gives authors who have been questions and editors who are defensive of their work, no matter how incompetent and inept it may be, the last word. But there is always the force of social media- tweets and blogs.

The critics were actually much too kind and restrained in a critique narrowly based on re-analyses. They ignored so much about

  • The target paper as an underpowered feasibility study being passed off a source of estimates of what a sufficiently sized randomized trial would yield.
  • The continuity between the mischief done in this article with tricks and spin in the past work of the author Turkington.
  • The laughably inaccurate lecture of the editor.
  • The lowlife journal in which the article was published.

These problems deserve a more unrestrained and thorough trashing. Journals may not yet be self-correcting, but blogs can do a reasonable job of exposing bad science.

Science needs vigilantes, because of the intransigence of those pumping crap into the literature.

Coming up next

In my next issue of Mind the Brain I’m going to team up with Magneto. You may recall I previously collaborated with him and Neurocritic to scrutinize some junk science that Jim Coan and Susan Johnson had published in PLOS One. Their article crassly promoted to clinicians what they claimed was a brain-soothing couples therapy. We obtained an apology and a correction in the journal for undeclared conflict of interest.

Magneto_430But that incident left Magneto upset with me. He felt I did not give sufficient attention to the continuity between how Coan had slipped post hoc statistical manipulations in the PLOS article to get positive results and what he had done in a past paper with Richard Davison. Worse, I had tipped off Jim Coan about our checking his work. Coan launched a pre-emptive tirade against post-publication scrutiny, his now infamous Negative Psychology rant  He focused his rage on Neuroskeptic, not Neurocritic or me, but the timing was not a coincidence. He then followed up by denouncing me on Facebook as the Chopra Deepak of skepticism.

I still have not unpacked that oxymoronic statement and decided if it was a compliment.

OK, Magneto, I will be less naïve and more thorough this round. I will pass on whatever you uncover.

Check back if you just want to augment your critical appraisal skills with some unconventional ones or if you just enjoy a spectacle. If you want to arrive at your own opinions ahead of time, email Douglas Turkington douglas.turkington@ntw.nhs.uk and for a PDF of his paywalled article. Tell him I said hello. The offer of a debate still stands.